Research Article

Plaque Index and Gingival Index Evaluation in Subjects with Gingivitis after Two Months of Treatment with Two Different Probiotic Food Supply: A Retrospective Study

Michela Zago
Sant'Andrea Hospital, Italy
Lorenzo Santi
Sant'Andrea Hospital, Italy
Maria Luisa Caimi
Sant'Andrea Hospital, Italy
Francesco Cavarra
University of Eastern Piedmont, Italy
Vincenzo Rocchetti
University of Eastern Piedmont, Italy
Edoardo Bianco
University of Milano Bicocca, Italy
* Corresponding author
DOI icon 10.24018/ejdent.2021.2.2.42

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Submitted 2021-02-19
Published 2021-03-26

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Article Main Content

Objective: The purpose of this study is to investigate and compare the Gingival Index and the Plaque Index in a population treated with 2 probiotic food supplies (Reuterin Os® and Carioblis®) for two months.

Material and Methods: The sample was composed of 92 patients suffering from gingivitis, divided into 4 groups: the first received only causal treatment (group A – control group), the second and the third (group B and C – test group) took respectively 1 and 2 tablet of probiotic food supplement Ruterin Os® every day for 60 days, the fourth (group D– test group) took 1 tablet of probiotic food supplement Carioblis® every day for 60 days.

The patients were visited every 14 days. Statistical analysis was performed to compare the control group to test groups after 2 months and to compare each index from the beginning to the end of treatment.

Result: The study showed that the use of the probiotics RuterinOs® or Carioblis® in combination with causal treatment in patients with gingivitis led to a statistically significant improvement in plaque indices (PI) and gingival inflammation indices (GI) compared to the control group subjected only to causal treatment. The analysis of the data also highlighted a better result for patients who took 1 tablet of RuterinOs® every day for 2 months.

Conclusion: The Authors can deduce that the somministration of one daily tablet of ReuterinOs® can bring benefits to oral health.

Keywords: Lactobacillus reuteri, gingivitis, probiotic, plaque

References

  1. Bizzin, B., Pizzo, G., Scapagnini, G. Nuzzo, D., Vasto, S. 2012. Probiotics and Oral Health. Current pharmaceutical design. 18, 5522-5531.
     Google Scholar
  2. Grellmann, A.P,. Zanatta, F.B., 2016. Diagnosis of gingivitis: state of the art. Journal of Dentistry & Oral Disorders 2, 1-8.
     Google Scholar
  3. Page, R.C. 1986. Gingivitis. Clin Periodontol. 13, 345-59.
     Google Scholar
  4. Verma, D., Jhawar, A., Khinda, N., Anand, D. 2014. Gingival diseases in childhood: A review. Global Journal of Medical Research. 14, 16-22.
     Google Scholar
  5. Singh, B., Singh, R., 2013. Gingivitis- A silent disease. Journal of Dental and Medical Sciences. 6, 30-33.
     Google Scholar
  6. Kistler, J.O., Booth, V., Bradshaw, D.J., Wade, W.G. 2013. Bacterial community development in experimental gingivitis. PLoS One 8, 1-13.
     Google Scholar
  7. Bianco, E., Maddalone, M., Porcaro, G., Amosso, E., Baldoni, M., 2019. Treatment of Osteoradionecrosis of the Jaw with Ozone in the Form of Oil-based Gel: 1-year follow-up. J Contemp Dent Pract. 20, 270-276.
     Google Scholar
  8. Shaw, L., Harjunmaa, U., Doyle, R., Mulewa, S., Charlie, D., Maleta, K., Callard, R., Walker, A.S., Balloux, F., Ashorn, P., Klein, N. 2016. Distinguishing the Signals of Gingivitis and periodontitis in supragingival plaque: a cross-sectional cohort study in Malawi. Appl Environ Microbiol 82, 6057-6067.
     Google Scholar
  9. Rastogi, P., Saini, H., Dixit, J., Singhal, R. 2011. Probiotics and oral health. National Journal of Maxillofacial Surgery. 2, 6-9.
     Google Scholar
  10. Segura, V., Ilyina, A., Segura, C.E., Belmares, Y.S. 2015. Etiology and microbiology of periodontal diseases: A Review. African Journal of Microbiology Research 9, 2300-2306.
     Google Scholar
  11. Barbato, L., Francioni, E., Bianchi, M., Mascitelli, E., Marco, L.B., Tonelli, D.P. 2015. Periodontitis and bone metabolism. Clin Cases Miner Bone Metab. 12, 174-7.
     Google Scholar
  12. Arunachalam, R., Rajeev, V. 2017. Communicative and Psychologic Management Protocol for Aggressive Periodontitis. World J Dent 8, 67-70.
     Google Scholar
  13. Caglar, E., Kargul, B., Tanboga, I. 2005. Bacteriotherapy and probiotics’ role on oral health. Oral Diseases. 11, 131–137.
     Google Scholar
  14. Wescombe, P.A., Heng, N.C.K., Burton, J.P., Chilcott C.N., Tagg, J.R. 2009. Streptococcal bacteriocins and the case for Streptococcus salivarius as model oral probiotics. Future Microbiology 4, 819-835.
     Google Scholar
  15. Gillor, O., Etzion, A., Riley, M.A. 2008. The dual role of bacteriocins as anti- and probiotics. Applied Microbiology and Biotechnology 81, 591-606.
     Google Scholar
  16. Kalate, F.A., Gholami, L., Alijani, E., Hedayatipanah, M., Kosari, S. 2018. Level of Interleukin-17 in Gingival Crevicular Fluid of Patients with Chronic Periodontitis. World J Dent 9, 495-499.
     Google Scholar
  17. Stamatova, I., Meurman, H. 2009. Probiotics: Health benefits in the mouth. American Journal of Dentistry. 22, 330-338.
     Google Scholar
  18. Yanine, N., Araya, I., Brignardello-Petersen, R., Carrascl-Labra, A., Gonzales, A., Preciado, A., Villanueva, J., Sanz, M., Martin, C. 2013. Effects of probiotics in periodontal diseases: a systematic review. Clinical Oral Investigation. 17, 1627–1634.
     Google Scholar
  19. Meurman, J.H., Stamatova, I. 2007. Probiotics: contributions to oral health. Oral Diseases. 13, 443–451.
     Google Scholar
  20. Yao, S.G., Fine, J.B. 2014. Probiotics for Bacterial Disease Treatment in the Oral Environment. Compendium of continuing education in dentistry. 35, 658-663.
     Google Scholar
  21. Paineau, D., Carcano, D., Leyer, G., Darqui, S., Alyanakian, M.A., Simoneau, G., Bergmann, J.F., Brassart, D., Bornet, F., Ouwehand, A.C. 2008. Effects of seven potential probiotic strains on specific immune responses in healthy adults: a double-blind, randomized, controlled trial. Immunology and Medical Microbioogy. 53, 107-113.
     Google Scholar
  22. Doron, S., Gorbach, S.L. 2006. Probiotics: their role in the treatment and prevention of disease. Expert Review of Anti- Infective Therapy. 4, 261–275.
     Google Scholar
  23. Centers for Disease Control and Prevention 2019. Oral Health Surveillance Report: Trends in Dental Caries and Sealants, Tooth Retention, and Edentulism, United States, 1999–2004 to 2011–2016. Atlanta, GA: Centers for Disease Control and Prevention, US Dept of Health and Human Services.
     Google Scholar
  24. Bianco, E., Rota, D. 2018 Oral findings in Rett syndrome: An update and review of the literature. Dent Med Probl. 55, 441-445.
     Google Scholar
  25. Haydari, M., Bardakci, A.G., Koldsland, O.C., Aass, A.M., Sandvik, L., Preu H.R., 2017. Comparing the effect of 0.06% -, 0.12% and 0.2% Chlorhexidine on plaque, bleeding and side effects in an experimental gingivitis model: a parallel group, double masked randomized clinical trial. BMC Oral Health. 17, 118-125.
     Google Scholar
  26. Li, Y., Lee, S., Hujoel, P., Su, M., Zhang, W., Kim, J., Zhang, Y.P., DeVizio, W. 2010. Prevalence and severity of gingivitis in American adults. Am J Dent. 23, 9-13.
     Google Scholar
  27. Mobini, R., Tremaroli, V., Ståhlman, M., Karlsson, F., Levin, M., Ljungberg, M., Sohlin, M., Bertéus Forslund, H., Perkins, R., Bäckhed, F., Jansson, PA. 2017. Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled trial. Diabetes Obes Metab. 19, 579-589.
     Google Scholar
  28. Bianco, E. 2016. Factors Influencing Immediate Maxillary Dental Implant Placement and Bone Resorption: A Review of the Literature and an Outlook on the Clinical Possibilities Dent Med Probl. 53, 408–412.
     Google Scholar
  29. Raff, A., Hunt, L.C. 2012. Probiotics for Periodontal Health: A Review of the Literature. The Journal of Dental Hygiene. 86, 71-81.
     Google Scholar
  30. Disale, P.R., Zope, S., Suragimath, G., Varma, A.S., Pisal, A. 2019. Toll-like Receptors: Molecular Microbe Sensors in Periodontium. World J Dent 10, 396–401.
     Google Scholar
  31. Jamali, Z., Alipour, M., Ebrahimi, S., Aghazadeh, M. 2019. Effect of Halita mouthwash on oral halitosis treatment: A randomized triple-blind clinical trial J Dent Res Dent Clin Dent Prospects. 13, 31-35.
     Google Scholar